Public RNA-seq Allele-Specific Expression (ASE) browser

We have performed Allele Specific Expression (ASE) mapping on 1,262 human public RNA-seq samples (manuscript preprint). We have identified 71,214 genetic variants showing significant (FDR ≤ 0.05) ASE. These variants can be queried using this website.

We have also made the other results and datasets from our manuscript available.

ASE browsers

Click here to browse all significant ASE effects or use the search box below. Note: all positions are build 37 coordinates

Search options:

• Ensembl gene identifier (ENSG00000009724)
• Gene symbol (MASP2)
• SNP RS number (rs72550870)
• Chrom:Pos (1:11106666)
• Chrom:Start-Stop (1:11100000-11200000)s

eQTL results

• Bladder eQTLs (FDR ≤ 0.05)
• Brain eQTLs (FDR ≤ 0.05)
• Breast eQTLs (FDR ≤ 0.05)
• Liver eQTLs (FDR ≤ 0.05)
• All samples eQTLs (FDR ≤ 0.05)

Data for the 4,978 samples used for expression clustering

• Raw expression matrix
• Normalized covariate corrected expression matrix
• Expression PCA - Eigenvectors
• Expression PCA - Principal components
• Expression PCA - Eigenvalues

Data for the 1,262 unique samples used for ASE and eQTL analyses

• Raw expression matrix
• Normalized expression matrix

The genotype data is available upon request, please e-mail  patrick  deelen  at  gmail dot com or dasha  zhernakova  at  gmail dot com