probeID ProbeChr Gene Probe_bp topSNP topSNP_chr topSNP_bp A1 A2 Freq b_GWAS se_GWAS p_GWAS b_eQTL se_eQTL p_eQTL b_SMR se_SMR p_SMR p_HEIDI nsnp_HEIDI ENSG00000237491 1 ENSG00000237491 729801 rs12184325 1 754105 T C 0.0247253 0.1277 0.044 3.727000e-03 0.516374 0.025345 2.856287e-92 0.247301 0.0860697 4.062513e-03 1.232433e-01 11 ENSG00000225880 1 ENSG00000225880 762244 rs114525117 1 759036 A G 0.0242674 0.0982 0.0436 2.421000e-02 0.429814 0.0256302 4.058700e-63 0.228471 0.10235 2.559840e-02 4.836869e-03 13 ENSG00000228794 1 ENSG00000228794 778907 rs60320384 1 769223 G C 0.175824 0.0248 0.0213 2.445000e-01 -0.0723327 0.010398 3.490792e-12 -0.34286 0.298569 2.508260e-01 6.039732e-01 20 ENSG00000188976 1 ENSG00000188976 887136 rs1806780 1 872352 C G 0.342033 0.008 0.0169 6.367000e-01 -0.112003 0.00832663 3.029183e-41 -0.0714266 0.150982 6.361562e-01 9.039605e-01 20 ENSG00000187961 1 ENSG00000187961 898531 rs10465242 1 886788 G A 0.278846 0.0152 0.024 5.279000e-01 -0.11512 0.00880998 5.083154e-39 -0.132036 0.208723 5.270009e-01 6.114075e-01 20 ENSG00000187583 1 ENSG00000187583 906561 rs9697711 1 900972 T G 0.0659341 0.0414 0.0321 1.967000e-01 -0.233405 0.0159084 9.771909e-49 -0.177374 0.13806 1.988743e-01 9.011614e-01 17 ENSG00000187642 1 ENSG00000187642 914038 rs9697711 1 900972 T G 0.0659341 0.0414 0.0321 1.967000e-01 -0.146333 0.0159411 4.326975e-20 -0.282917 0.221518 2.015403e-01 8.680022e-01 17 ENSG00000188290 1 ENSG00000188290 934947 rs2710882 1 930923 A G 0.224359 -0.0081 0.0185 6.631000e-01 0.333929 0.00930974 9.366628e-282 -0.0242566 0.0554051 6.615275e-01 7.185732e-01 20 ENSG00000187608 1 ENSG00000187608 949361 rs2799069 1 950716 A T 0.0879121 0.0373 0.0373 3.163000e-01 -0.285225 0.0138976 1.330674e-93 -0.130774 0.130929 3.178843e-01 9.395904e-01 20 ENSG00000188157 1 ENSG00000188157 973499 rs2710869 1 938116 T G 0.0815018 0.0362 0.0376 3.348000e-01 -0.0889356 0.0144695 7.926115e-10 -0.407036 0.427933 3.415192e-01 9.659997e-01 17 ENSG00000217801 1 ENSG00000217801 999924 rs4970401 1 1001177 G C 0.272436 0.0005 0.0149 9.720000e-01 0.397161 0.0086148 0.000000e+00 0.00125893 0.0375162 9.732304e-01 9.985062e-01 20 ENSG00000131591 1 ENSG00000131591 1034469 rs79211741 1 1034243 T C 0.131868 -0.0133 0.0188 4.796000e-01 -0.212894 0.0116468 1.211902e-74 0.0624723 0.0883728 4.796177e-01 2.339563e-01 20 ENSG00000223823 1 ENSG00000223823 1075916 rs10907183 1 1071118 G C 0.479396 0.0038 0.0144 7.911000e-01 0.114521 0.00790334 1.397402e-47 0.0331817 0.125762 7.918993e-01 5.785731e-01 20 ENSG00000186891 1 ENSG00000186891 1140479 rs3813201 1 1151232 C T 0.215201 -0.0675 0.0182 2.115000e-04 -0.266157 0.00952301 6.817646e-172 0.25361 0.0689802 2.363985e-04 3.495820e-01 20 ENSG00000186827 1 ENSG00000186827 1148112 rs7536568 1 1171683 G A 0.141026 -0.0635 0.0202 1.703000e-03 -0.268701 0.0112813 2.163753e-125 0.236322 0.0758285 1.829882e-03 4.710549e-01 20 ENSG00000078808 1 ENSG00000078808 1159849 rs78479912 1 1151917 A G 0.0407509 -0.1002 0.0365 6.078000e-03 -0.548575 0.0197984 5.592604e-169 0.182655 0.0668618 6.298358e-03 1.651652e-01 20 ENSG00000176022 1 ENSG00000176022 1169025 rs78107697 1 1161866 T C 0.124084 -0.0611 0.02 2.194000e-03 -0.661998 0.011429 0.000000e+00 0.0922963 0.0302535 2.282632e-03 3.485365e-01 20 ENSG00000230415 1 ENSG00000230415 1213201 rs6603785 1 1186502 T A 0.234432 -0.0834 0.0192 1.396000e-05 -0.0618671 0.00934407 3.567804e-11 1.34805 0.371169 2.813364e-04 7.708202e-01 20 ENSG00000162572 1 ENSG00000162572 1221612 rs6662635 1 1220425 G A 0.0723443 -0.1106 0.0532 3.771000e-02 -0.164388 0.0152632 4.759691e-27 0.672799 0.329599 4.122433e-02 4.500787e-01 20 ENSG00000169972 1 ENSG00000169972 1245502 rs12410087 1 1239935 C A 0.141484 -0.0655 0.0209 1.677000e-03 -0.148195 0.0113355 4.660633e-39 0.441984 0.145026 2.306544e-03 7.169082e-01 20 ENSG00000240731 1 ENSG00000240731 1253515 rs4970439 1 1298411 C T 0.158883 -0.0818 0.0256 1.392000e-03 0.0707484 0.0108291 6.437902e-11 -1.15621 0.402805 4.099622e-03 9.300135e-01 20 ENSG00000127054 1 ENSG00000127054 1253518 rs307357 1 1281345 C T 0.158883 -0.0825 0.0259 1.417000e-03 0.173281 0.0107925 5.223105e-58 -0.476106 0.152382 1.781482e-03 8.342444e-01 20 ENSG00000224051 1 ENSG00000224051 1262206 rs307354 1 1264539 G C 0.130037 -0.0669 0.0297 2.455000e-02 0.321774 0.0116387 3.040985e-168 -0.20791 0.0926067 2.476261e-02 2.518862e-01 20 ENSG00000169962 1 ENSG00000169962 1268690 rs307354 1 1264539 G C 0.130037 -0.0669 0.0297 2.455000e-02 0.225656 0.0117095 9.373640e-83 -0.296469 0.132512 2.526714e-02 2.378736e-01 20 ENSG00000224870 1 ENSG00000224870 1336164 rs2985898 1 1318351 T C 0.0393773 -0.0707 0.0418 9.042000e-02 -0.34205 0.0202771 7.633055e-64 0.206695 0.122817 9.238498e-02 5.360457e-02 20 ENSG00000242485 1 ENSG00000242485 1339990 rs12408158 1 1238492 A G 0.141026 -0.0701 0.0208 7.456000e-04 0.183486 0.011335 6.168792e-59 -0.382046 0.115791 9.687698e-04 1.275966e-01 20 ENSG00000235098 1 ENSG00000235098 1355474 rs2260424 1 1314714 A G 0.181319 -0.0904 0.0247 2.453000e-04 -0.0987513 0.0102665 6.660388e-22 0.915431 0.267618 6.246754e-04 8.095197e-01 20 ENSG00000215915 1 ENSG00000215915 1395303 rs74706549 1 1513736 G A 0.0132784 -0.0463 0.0573 4.193000e-01 -0.267097 0.0345747 1.116800e-14 0.173346 0.215699 4.216027e-01 5.712643e-01 17 ENSG00000160072 1 ENSG00000160072 1420185 rs74706549 1 1513736 G A 0.0132784 -0.0463 0.0573 4.193000e-01 -0.348116 0.0345517 7.111591e-24 0.133002 0.165129 4.205648e-01 4.453245e-01 17 ENSG00000197785 1 ENSG00000197785 1458799 rs9439469 1 1507366 A G 0.481227 -0.0448 0.0139 1.279000e-03 -0.103394 0.00790695 4.492205e-39 0.433292 0.13846 1.751830e-03 3.476277e-01 20 ENSG00000160075 1 ENSG00000160075 1493651 rs9439469 1 1507366 A G 0.481227 -0.0448 0.0139 1.279000e-03 0.453924 0.00750926 0.000000e+00 -0.0986949 0.0306654 1.288854e-03 2.457110e-01 20 ENSG00000215014 1 ENSG00000215014 1510864 rs7518083 1 1509156 G A 0.267857 -0.0361 0.0155 1.972000e-02 0.189339 0.00888199 7.862560e-101 -0.190663 0.0823508 2.059899e-02 5.420178e-02 17 ENSG00000228594 1 ENSG00000228594 1534434 rs4648787 1 1522006 T C 0.308608 0.0034 0.0175 8.454000e-01 0.0738176 0.00856591 6.837206e-18 0.0460595 0.237131 8.459908e-01 9.059592e-02 7 ENSG00000197530 1 ENSG00000197530 1558392 rs72634811 1 1529994 C G 0.180861 0.0206 0.0179 2.496000e-01 0.116414 0.010271 8.884070e-30 0.176955 0.154552 2.522294e-01 2.922557e-01 9 ENSG00000248333 1 ENSG00000248333 1580538 rs11486028 1 1674677 C G 0.341117 0.0507 0.0139 2.766000e-04 -0.122328 0.00832742 7.493480e-49 -0.414459 0.117079 4.001444e-04 4.751604e-02 20 ENSG00000269737 1 ENSG00000269737 1604139 rs72634811 1 1529994 C G 0.180861 0.0206 0.0179 2.496000e-01 0.0623426 0.0102859 1.352801e-09 0.330432 0.292253 2.582079e-01 6.172837e-01 7 ENSG00000189339 1 ENSG00000189339 1608553 rs72634811 1 1529994 C G 0.180861 0.0206 0.0179 2.496000e-01 -0.188837 0.0102371 5.573686e-76 -0.109089 0.0949752 2.507190e-01 1.534132e-03 20 ENSG00000215914 1 ENSG00000215914 1632309 rs601141 1 1627805 A C 0.485806 0.0296 0.0154 5.480000e-02 -0.0735251 0.00791495 1.551609e-20 -0.402584 0.213889 5.980758e-02 7.230753e-03 20 ENSG00000008128 1 ENSG00000008128 1644967 rs141694617 1 1776991 T G 0.0141941 0.1583 0.0596 7.940000e-03 0.345256 0.0334324 5.319837e-25 0.4585 0.178243 1.010181e-02 NA NA ENSG00000268575 1 ENSG00000268575 1651651 rs11486028 1 1674677 C G 0.341117 0.0507 0.0139 2.766000e-04 -0.240553 0.00824624 4.498833e-187 -0.210765 0.0582335 2.954020e-04 3.563293e-03 20 ENSG00000227775 1 ENSG00000227775 1662320 rs72634811 1 1529994 C G 0.180861 0.0206 0.0179 2.496000e-01 0.197152 0.0102322 1.000996e-82 0.104488 0.0909548 2.506423e-01 1.281510e-04 20 ENSG00000215790 1 ENSG00000215790 1666854 rs141694617 1 1776991 T G 0.0141941 0.1583 0.0596 7.940000e-03 0.251674 0.0334584 5.394497e-14 0.628988 0.251144 1.226270e-02 NA NA ENSG00000008130 1 ENSG00000008130 1697283 rs12729990 1 1812035 T A 0.594322 -0.0591 0.0126 2.588000e-06 0.0529371 0.00806206 5.161501e-11 -1.11642 0.292508 1.352451e-04 4.454459e-02 20 ENSG00000231050 1 ENSG00000231050 1823503 rs6687065 1 1778469 A G 0.603022 -0.0624 0.0124 5.430000e-07 -0.254417 0.00796983 1.301290e-223 0.245267 0.0493408 6.665204e-07 9.461052e-01 20 ENSG00000169885 1 ENSG00000169885 1847500 rs28508199 1 1852484 G A 0.419414 -0.0591 0.0138 1.817000e-05 0.0960237 0.00800945 4.067476e-33 -0.615473 0.152609 5.506533e-05 2.017423e-01 20 ENSG00000187730 1 ENSG00000187730 1956486 rs6663186 1 1938473 G T 0.154762 0.0003 0.0215 9.878000e-01 0.13275 0.0109272 5.835571e-34 0.00225988 0.161958 9.888671e-01 9.237719e-01 19 ENSG00000067606 1 ENSG00000067606 2049371 rs626479 1 2110260 A G 0.236264 -0.0054 0.0139 6.973000e-01 -0.14586 0.00928941 1.470130e-55 0.0370217 0.0953257 6.977420e-01 7.456863e-01 20 ENSG00000182873 1 ENSG00000182873 2114530 rs2503701 1 2121118 C T 0.311813 0.0049 0.0142 7.310000e-01 -0.162751 0.00850256 1.141619e-81 -0.0301074 0.0872641 7.300836e-01 2.275764e-01 20 ENSG00000269554 1 ENSG00000269554 2122208 rs11587831 1 2110848 G T 0.135073 -0.0068 0.0158 6.692000e-01 -0.0821179 0.0115799 1.327599e-12 0.0828078 0.19276 6.674944e-01 9.250572e-01 20 ENSG00000162585 1 ENSG00000162585 2130031 rs11587831 1 2110848 G T 0.135073 -0.0068 0.0158 6.692000e-01 -0.423911 0.0113435 1.178192e-305 0.0160411 0.0372744 6.669402e-01 9.684314e-01 20 ENSG00000157933 1 ENSG00000157933 2200846 rs263535 1 2177727 C T 0.369505 -0.0107 0.0128 4.029000e-01 0.0740153 0.0081966 1.716709e-19 -0.144565 0.173677 4.051954e-01 7.515717e-01 20 ENSG00000269896 1 ENSG00000269896 2283056 rs7545940 1 2299627 C T 0.371337 0.0086 0.0129 5.035000e-01 -0.17763 0.00813803 1.280278e-105 -0.0484152 0.0726566 5.051836e-01 9.971739e-01 20 ENSG00000116151 1 ENSG00000116151 2287919 rs7545940 1 2299627 C T 0.371337 0.0086 0.0129 5.035000e-01 -0.147928 0.00815661 1.656622e-73 -0.0581363 0.0872634 5.052726e-01 9.906490e-01 20 ENSG00000178642 1 ENSG00000178642 2318366 rs61760819 1 2311393 G A 0.201465 -0.0172 0.0149 2.457000e-01 -0.157216 0.00983668 1.689526e-57 0.109404 0.0950211 2.495828e-01 1.906799e-01 20 ENSG00000157916 1 ENSG00000157916 2329228 rs12031614 1 2306152 T C 0.403846 0.0113 0.0128 3.755000e-01 -0.0733824 0.00806276 8.917518e-20 -0.153988 0.175247 3.795701e-01 9.847072e-01 20 ENSG00000157911 1 ENSG00000157911 2340736 rs12092052 1 2340504 T C 0.309066 0.0006 0.014 9.687000e-01 0.11593 0.00854766 6.654552e-42 0.00517553 0.120763 9.658156e-01 5.258086e-01 20 ENSG00000149527 1 ENSG00000149527 2397194 rs67658905 1 2347576 T G 0.197802 0.0267 0.0178 1.328000e-01 0.615964 0.00932651 0.000000e+00 0.0433467 0.0289052 1.337146e-01 1.960190e-01 20 ENSG00000224387 1 ENSG00000224387 2424218 rs12731309 1 2352146 T C 0.201007 0.0272 0.0177 1.247000e-01 0.118746 0.00986215 2.173684e-33 0.22906 0.150266 1.274193e-01 6.650652e-01 20 ENSG00000229393 1 ENSG00000229393 2425397 rs12731309 1 2352146 T C 0.201007 0.0272 0.0177 1.247000e-01 0.0951072 0.00987019 5.645115e-22 0.285993 0.188458 1.291290e-01 5.756445e-01 13 ENSG00000157881 1 ENSG00000157881 2449005 rs2985862 1 2452569 T C 0.155678 0.0423 0.0143 3.095000e-03 0.220265 0.0108564 1.608327e-91 0.192042 0.0656082 3.421433e-03 4.761914e-04 20 ENSG00000238164 1 ENSG00000238164 2484914 rs74466775 1 2553657 T C 0.0311355 -0.0214 0.0314 4.957000e-01 -0.34352 0.0227259 1.274109e-51 0.0622962 0.0914995 4.959746e-01 7.674148e-03 9 ENSG00000157873 1 ENSG00000157873 2491949 rs3748825 1 2483270 C T 0.547619 0.0632 0.0125 4.436000e-07 0.337011 0.00773155 0.000000e+00 0.187531 0.0373394 5.104913e-07 8.387992e-01 20 ENSG00000225931 1 ENSG00000225931 2503330 rs74466775 1 2553657 T C 0.0311355 -0.0214 0.0314 4.957000e-01 0.207121 0.0227781 9.634281e-20 -0.103321 0.152027 4.967436e-01 9.207318e-03 7 ENSG00000228037 1 ENSG00000228037 2514485 rs74466775 1 2553657 T C 0.0311355 -0.0214 0.0314 4.957000e-01 0.339742 0.022728 1.600189e-50 -0.0629889 0.092519 4.959845e-01 8.701339e-02 5 ENSG00000157870 1 ENSG00000157870 2520419 rs10797434 1 2511280 T C 0.571429 0.0583 0.0123 2.307000e-06 -0.291232 0.00783662 2.703463e-302 -0.200184 0.0425765 2.579410e-06 1.956292e-02 20 ENSG00000142606 1 ENSG00000142606 2543279 rs10752747 1 2524915 T G 0.43315 0.0383 0.0132 3.568000e-03 -0.26186 0.00785858 1.885421e-243 -0.146262 0.0505995 3.845350e-03 1.264790e-03 20 ENSG00000215912 1 ENSG00000215912 2642850 rs6657596 1 2703107 G T 0.391484 0.0385 0.0133 3.813000e-03 0.124705 0.00808598 1.157214e-53 0.308728 0.108514 4.440378e-03 1.510124e-03 20 ENSG00000162591 1 ENSG00000162591 3467271 rs2794365 1 3437935 T C 0.505952 -0.0135 0.0144 3.512000e-01 0.13625 0.0078863 7.034332e-67 -0.0990825 0.105843 3.492100e-01 4.816973e-01 20 ENSG00000158109 1 ENSG00000158109 3544128 rs80303864 1 3576662 T A 0.907051 -0.0462 0.0225 3.961000e-02 0.160497 0.0136132 4.405873e-32 -0.287857 0.1423 4.308520e-02 4.382491e-02 15 ENSG00000116213 1 ENSG00000116213 3558328 rs12757620 1 3540024 G T 0.38141 -0.0097 0.013 4.566000e-01 0.332212 0.00794006 0.000000e+00 -0.0291982 0.0391379 4.556461e-01 6.441488e-01 20 ENSG00000078900 1 ENSG00000078900 3610924 rs1885864 1 3554988 T C 0.203755 -0.0065 0.0154 6.732000e-01 -0.0537073 0.00982966 4.660491e-08 0.121026 0.287594 6.738835e-01 3.556136e-01 11 ENSG00000227372 1 ENSG00000227372 3658224 rs72637004 1 3661249 G A 0.263278 -0.0082 0.0136 5.479000e-01 0.217427 0.00891169 1.795863e-131 -0.0377138 0.0625687 5.466703e-01 4.634828e-01 20 ENSG00000235169 1 ENSG00000235169 3690949 rs1891934 1 3694796 A G 0.167582 0.0115 0.0147 4.362000e-01 0.882136 0.00938429 0.000000e+00 0.0130365 0.0166647 4.340466e-01 9.146935e-01 20 ENSG00000130764 1 ENSG00000130764 3704926 rs113736419 1 3705211 G A 0.0155678 -0.0155 0.0387 6.897000e-01 0.482644 0.0318842 9.177029e-52 -0.0321148 0.0802114 6.888791e-01 6.410934e-01 9 ENSG00000116198 1 ENSG00000116198 3751211 rs6424058 1 3747580 T C 0.36859 0.0043 0.0124 7.314000e-01 0.684162 0.00726183 0.000000e+00 0.00628506 0.0181245 7.287627e-01 7.326399e-01 20 ENSG00000169598 1 ENSG00000169598 3787919 rs7552969 1 3741782 C T 0.427656 0.0056 0.0123 6.490000e-01 0.0782801 0.00799495 1.228300e-22 0.071538 0.157298 6.492581e-01 4.106448e-01 20 ENSG00000198912 1 ENSG00000198912 3811273 rs35583447 1 3829614 A G 0.288462 0.0234 0.015 1.175000e-01 -0.443692 0.00838289 0.000000e+00 -0.0527393 0.0338219 1.189200e-01 3.413019e-01 20 ENSG00000236423 1 ENSG00000236423 3825362 rs12741752 1 3817252 C T 0.0705128 0.0004 0.0241 9.873000e-01 0.142322 0.0154529 3.261219e-20 0.00281054 0.169335 9.867577e-01 4.299627e-01 20 ENSG00000196581 1 ENSG00000196581 4779321 rs76270994 1 4811999 T C 0.158883 0.0202 0.0149 1.761000e-01 0.0898081 0.0108244 1.069499e-16 0.224924 0.16811 1.809093e-01 5.353184e-01 20 ENSG00000131697 1 ENSG00000131697 5987702 rs12745395 1 6029937 A G 0.501374 0.0083 0.0126 5.138000e-01 0.308561 0.0077317 0.000000e+00 0.0268991 0.0408403 5.101267e-01 6.403210e-01 20 ENSG00000069424 1 ENSG00000069424 6106389 rs60876998 1 6087241 A T 0.457418 0.0126 0.0126 3.206000e-01 -0.23092 0.0078455 2.053529e-190 -0.0545644 0.0545959 3.175897e-01 4.860055e-01 20 ENSG00000116254 1 ENSG00000116254 6201018 rs17436816 1 6204161 A G 0.0782967 0.0022 0.0205 9.159000e-01 -0.103431 0.0147342 2.221902e-12 -0.0212702 0.198223 9.145474e-01 7.755669e-01 12 ENSG00000116251 1 ENSG00000116251 6255389 rs113782549 1 6233266 A G 0.100275 0.0386 0.0322 2.308000e-01 -0.132811 0.013167 6.332487e-24 -0.29064 0.244157 2.338969e-01 7.704684e-01 20 ENSG00000158286 1 ENSG00000158286 6273447 rs4908864 1 6263354 T C 0.306319 0.0321 0.0144 2.594000e-02 -0.258346 0.00847071 2.711270e-204 -0.124252 0.0558879 2.619989e-02 8.914232e-01 20 ENSG00000116237 1 ENSG00000116237 6288642 rs12073932 1 6293890 A G 0.0737179 0.0389 0.0332 2.405000e-01 -0.558208 0.0148332 6.348787e-310 -0.0696873 0.0595049 2.415508e-01 4.363745e-01 20 ENSG00000158292 1 ENSG00000158292 6314220 rs56235663 1 6355066 G A 0.0210623 0.1014 0.031 1.069000e-03 -0.263335 0.0275473 1.184400e-21 -0.385061 0.124421 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